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Jorma Keski-Oja Selected Research

Membrane-Associated Matrix Metalloproteinases

5/2015MMP16 Mediates a Proteolytic Switch to Promote Cell-Cell Adhesion, Collagen Alignment, and Lymphatic Invasion in Melanoma.
1/2011Membrane-type-3 matrix metalloproteinase (MT3-MMP) functions as a matrix composition-dependent effector of melanoma cell invasion.
3/2004Co-recycling of MT1-MMP and MT3-MMP through the trans-Golgi network. Identification of DKV582 as a recycling signal.

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Jorma Keski-Oja Research Topics

Disease

19Neoplasms (Cancer)
12/2018 - 07/2002
6Glioblastoma (Glioblastoma Multiforme)
12/2018 - 03/2012
4Melanoma (Melanoma, Malignant)
05/2015 - 07/2003
4Carcinoma (Carcinomatosis)
07/2012 - 07/2002
3Neoplasm Metastasis (Metastasis)
05/2015 - 09/2010
3Chronic Obstructive Pulmonary Disease (COPD)
03/2010 - 02/2008
2Glioma (Gliomas)
01/2017 - 08/2009
2Retinal Perforations
06/2014 - 09/2013
2Carcinogenesis
02/2011 - 09/2006
2Emphysema
03/2010 - 02/2008
2Osteosarcoma (Osteogenic Sarcoma)
12/2009 - 09/2002
2Fibrosarcoma
12/2008 - 03/2002
2Fibrosis (Cirrhosis)
02/2008 - 02/2008
2Pulmonary Fibrosis (Fibrosing Alveolitis)
02/2008 - 02/2008
2Colorectal Neoplasms (Colorectal Cancer)
10/2004 - 09/2002
1Retinal Detachment (Retinal Detachments)
06/2014
1Proliferative Vitreoretinopathy
06/2014
1Brain Neoplasms (Brain Tumor)
10/2013
1Diabetic Retinopathy (Retinopathy, Diabetic)
09/2013
1Hypoxia (Hypoxemia)
09/2013
1Nasopharyngeal Carcinoma
12/2012
1Lung Diseases (Lung Disease)
07/2012
1Asbestosis
07/2012
1Esophageal Squamous Cell Carcinoma
08/2011
1Mesothelioma
02/2011
1Malignant Mesothelioma
02/2011
1Adenocarcinoma
10/2010
1Pulmonary Emphysema
03/2010
1Airway Obstruction (Choking)
08/2009
1Disease Progression
02/2008
1Adenocarcinoma of Lung
09/2006
1Pathologic Processes
03/2004
1Cardiomyopathies (Cardiomyopathy)
09/2002
1Squamous Cell Neoplasms (Squamous Cell Cancer)
07/2002
1Wounds and Injuries (Trauma)
07/2002
1Skin Neoplasms (Skin Cancer)
07/2002

Drug/Important Bio-Agent (IBA)

10Proteins (Proteins, Gene)FDA Link
10/2013 - 03/2002
8Transforming Growth Factor beta (TGF-beta)IBA
03/2010 - 09/2002
5CollagenIBA
05/2015 - 06/2003
5Transforming Growth Factors (Transforming Growth Factor)IBA
06/2014 - 08/2009
5Carrier Proteins (Binding Protein)IBA
08/2011 - 09/2002
5Matrix Metalloproteinase 14 (MT1-MMP)IBA
01/2011 - 03/2002
4IntegrinsIBA
10/2013 - 07/2003
4Matrix Metalloproteinases (MMPs)IBA
09/2010 - 03/2002
3Netrin-1IBA
01/2017 - 06/2013
3Membrane-Associated Matrix MetalloproteinasesIBA
05/2015 - 03/2004
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
09/2013 - 07/2002
3EnzymesIBA
01/2011 - 07/2002
3EndostatinsIBA
03/2005 - 10/2002
3Collagen Type XVIII (Type XVIII Collagen)IBA
03/2005 - 10/2002
2Indicators and Reagents (Reagents)IBA
05/2015 - 08/2009
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2014 - 09/2013
2Angiopoietin-2IBA
06/2014 - 09/2013
2ErythropoietinFDA Link
06/2014 - 09/2013
2Angiopoietin-1IBA
06/2014 - 09/2013
2Matrix Metalloproteinase 9 (Gelatinase B)IBA
09/2013 - 07/2002
2Cadherins (E-Cadherin)IBA
07/2012 - 09/2006
2AsbestosIBA
07/2012 - 02/2008
2Biological ProductsIBA
08/2009 - 09/2006
2Latent TGF-beta Binding Proteins (Latent TGF beta Binding Protein)IBA
08/2009 - 10/2004
2AntibodiesIBA
07/2003 - 09/2002
1Epidermal Growth Factor (EGF)IBA
12/2018
1RNA (Ribonucleic Acid)IBA
12/2018
1Cell Adhesion MoleculesIBA
05/2015
1Membrane Proteins (Integral Membrane Proteins)IBA
05/2015
1Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA
05/2015
1EphrinsIBA
10/2013
1EphA1 Receptor (Eph Receptor)IBA
10/2013
1Eph Family Receptors (Eph Receptors)IBA
10/2013
1CytokinesIBA
09/2013
1Matrix Metalloproteinase 2 (Gelatinase A)IBA
09/2013
1Temozolomide (Temodar)FDA LinkGeneric
01/2013
1Pharmaceutical PreparationsIBA
01/2013
1MethyltransferasesIBA
01/2013
1Protein Isoforms (Isoforms)IBA
02/2011
1Small Interfering RNA (siRNA)IBA
02/2011
1Collagen Type I (Type I Collagen)IBA
01/2011
1FibrinIBA
01/2011
1Matrix Metalloproteinase 16IBA
01/2011
1Matrix Metalloproteinase 15IBA
01/2011
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
10/2010
1Type 4 Fibroblast Growth Factor ReceptorIBA
10/2010
1Phosphotransferases (Kinase)IBA
09/2010
1AntioxidantsIBA
03/2010
1TOR Serine-Threonine KinasesIBA
03/2010
1Fibrillin-1IBA
12/2009
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
02/2008
1Reactive Oxygen Species (Oxygen Radicals)IBA
02/2008
1LipidsIBA
03/2005
1Therapeutic UsesIBA
01/2005
1Heparin AntagonistsIBA
07/2003
1Monoclonal AntibodiesIBA
07/2003
1Integrin beta1IBA
07/2003
1Transforming Growth Factor beta1 (TGF beta 1)IBA
09/2002
1Messenger RNA (mRNA)IBA
09/2002
1collagenase 1IBA
07/2002
1Glutathione Transferase (Glutathione S-Transferase)IBA
03/2002

Therapy/Procedure

2Therapeutics
01/2017 - 01/2005
1Vitrectomy
09/2013